The EM Algorithm in Genetics, Genomics and Public Health
نویسنده
چکیده
The popularity of the EM algorithm owes much to the 1977 paper by Dempster, Laird and Rubin. That paper gave the algorithm its name, identified the general form and some key properties of the algorithm and established its broad applicability in scientific research. This review gives a nontechnical introduction to the algorithm for a general scientific audience, and presents a few examples characteristic of its application.
منابع مشابه
Artificial intelligence & genetics
Artificial intelligence (AI) is the development of computer systems that are able to perform tasks that normally require human intelligence. Artificial intelligence (AI) is a wide-ranging tool that enables people to rethink how we integrate information, analyze data, and use the resulting insights to improve decision making—and already it is transforming every walk of life. AI has application...
متن کاملEstimation of health effects attributed toNO2exposure from the use of AirQ model in Ahvaz
Background & objectives:AirQ software proved to be a valid and reliable tool to estimate the potential short term effects of air pollution. In this study the AirQ2.2.3 model was used to evaluate adverse health effects caused by nitrogen dioxide(NO2) exposure in Ahvaz during 2009. Materials & Methods:The AirQ,developed by the World Health Organization (WHO) to predi...
متن کاملVascular Endothelial Growth Factor (VEGF) Gene Promoter Polymorphisms and Disease Progression in North Indian Cohort with Autosomal Dominant Polycystic Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by a significant phenotypic variability in progression of the disease. Vascular endothelial growth factor (VEGF) has been reported to play a major role in renal pathophysiology. The aim of the present case-control study was to evaluate the association of two promoter polymorphisms (-2578C>A and -1154G>A) of VEGF gene and ADPK...
متن کاملThe Integration of Genomics into Public Health Research, Policy and Practice in the United States.
Objectives: To examine the opportunities for and responsibilities of the public health community in bridging the gap between gene discovery and the application of genetic information to improve health and prevent disease. Methods: We developed genetics-related definitions for the core functions and essential services of public health. We combined these definitions with a visual model to create ...
متن کاملBuilding capacity for human genetics and genomics research in Trinidad and Tobago.
Advances in human genetics and genomic sciences and the corresponding explosion of biomedical technologies have deepened current understanding of human health and revolutionized medicine. In developed nations, this has led to marked improvements in disease risk stratification and diagnosis. These advances have also led to targeted intervention strategies aimed at promoting disease prevention, p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011